Position
| Chromosome | chr1 |
| Start | 7574054 |
| End | 7602072 |
| Strand | - |
view in Gbrowse: chr1:7574054..7602072
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_028032124.1 | gamma-aminobutyric acid receptor subunit beta-like isoform X1 | 0.0 | 1003 |
ORF sequence (1449 bp)
ATGAGCGGCGCCAAGCCCCGCACCGCGCCGCTTCTGCTGGCGTTAGCGGCTACCTTCCTACCCCAAGTTGATCATGTAGCGGGCGCTGGTGGCGGTGGTATGTTTGGCGATGTTAATATATCGGCCATTTTGGATTCATTTAGTATTAGTTATGACAAAAGAGTAAGACCCAACTATGGAGGACCACCCGTGGAAGTGGGGGTTACCATGTACGTGCTCTCCATCAGCTCTCTGTCTGAAGTGAAAATGGACTTCACGTTGGACTTTTACTTCAGACAGTTTTGGACCGATCCGCGATTGGCGTACAAAAAAAGGACAGGAGTTGAAACGTTGTCGGTTGGCTCCGAATTCATAAAGAACATATGGGTGCCCGACACATTCTTTGTGAACGAAAAACAGTCTTATTTCCATATAGCTACGACAAGTAACGAATTTATACGTATACATTACTCTGGCTCAATAACTAGAAGTATAAGATTGACTATTACTGCGTCTTGTCCAATGAATCTGCAATACTTTCCAATGGATCGTCAATTATGCCATATAGAAATAGAAAGTTTCGGCTACACCATGCGGGACATCCGATACAAATGGAACGAGGGGCCCAACTCTGTGGGTGTTTCCAGCGAGGTGTCGCTACCGCAGTTCAAAGTCCTGGGTCACCGCCAACGAGCTATGGAGATCTCCCTCACAACAGGAAATTATTCAAGATTAGCATGTGAAATACAATTTGTGCGCTCTATGGGCTACTATCTAATCCAAATTTACATTCCATCGGGACTCATCGTGATCATATCCTGGGTGTCGTTTTGGTTGAACCGTAACGCCACTCCGGCTCGAGTGGCTCTCGGCGTCACCACTGTGCTGACAATGACAACGCTTATGTCATCGACGAACGCTGCCCTACCAAAAATTTCATACGTAAAATCAATTGACGTCTACTTAGGAACGTGTTTCGTAATGGTCTTCGCGAGTCTTTTAGAATACGCAACTGTCGGATATATGGCTAAGAGAATACAAATGAGGAAACAGCGATTTGTGGCTATACAGAAAATTGCCTCGGAGAAGAAACTTCCAGAATGCCCTCCAGTCGGCGATCCACACACTTTATCGAAGATGAATACTTTAAGCAGATGTCCTCCTAGCAGACCATCTGAAGTCCGTTTTAAAGTTCACGATCCGAAGGCGCATTCCAAAGGCGGTACTTTGGAGAACACCATTAACGGAGGAAGAGGGGGAGCAGACGAAGAAAATCCAGGTCCCCATCCAATACATCCAGGAAAGGATATTAGCAAACTACTGGGAATGACGCCATCAGACATCGACAAATATTCCCGTATAGTTTTCCCGGTTTGCTTCGTTTGTTTTAATCTTATGTATTGGATTATATACCTTCATGTTTCGGACGTCGTGGCTAACGATCTGGTTCTTCTGGAAGAAGATAAATAG
Protein sequence (482 aa)
MSGAKPRTAPLLLALAATFLPQVDHVAGAGGGGMFGDVNISAILDSFSISYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYKKRTGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRIHYSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVANDLVLLEEDK
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| Gene3D | 2.70.170.10 | - |
36 | 245 | 1.2e-75 |
IPR036734 |
| SUPERFAMILY | SSF63712 | - |
42 | 247 | 5.6e-56 |
IPR036734 |
| TIGRFAM | TIGR00860 | LIC: cation transporter family protein |
42 | 464 | 2.1e-119 |
IPR006201 |
| Pfam | PF02931 | Neurotransmitter-gated ion-channel ligand binding domain |
43 | 238 | 6.6e-50 |
IPR006202 |
| PANTHER | PTHR18945 | - |
50 | 186 | 2.1e-120 |
IPR006201 |
| PANTHER | PTHR18945:SF611 | - |
50 | 186 | 2.1e-120 |
- |
| CDD | cd19008 | LGIC_ECD_GABAR_RDL-like |
64 | 247 | 6.4e-134 |
- |
| ProSitePatterns | PS00236 | Neurotransmitter-gated ion-channels signature. |
166 | 180 | - |
IPR018000 |
| PANTHER | PTHR18945 | - |
187 | 387 | 2.1e-120 |
IPR006201 |
| PANTHER | PTHR18945:SF611 | - |
187 | 387 | 2.1e-120 |
- |
| SUPERFAMILY | SSF90112 | - |
248 | 469 | 8.5e-56 |
IPR036719 |
| CDD | cd19049 | LGIC_TM_anion |
250 | 347 | 1.7e-40 |
- |
| Pfam | PF02932 | Neurotransmitter-gated ion-channel transmembrane region |
255 | 412 | 7.2e-38 |
IPR006029 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR006029 | Neurotransmitter-gated ion-channel transmembrane domain |
| IPR006201 | Neurotransmitter-gated ion-channel |
| IPR006202 | Neurotransmitter-gated ion-channel ligand-binding domain |
| IPR018000 | Neurotransmitter-gated ion-channel, conserved site |
| IPR036719 | Neurotransmitter-gated ion-channel transmembrane domain superfamily |
| IPR036734 | Neurotransmitter-gated ion-channel ligand-binding domain superfamily |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0004888 | transmembrane signaling receptor activity |
| molecular function | GO:0005216 | ion channel activity |
| molecular function | GO:0005230 | extracellular ligand-gated ion channel activity |
| biological process | GO:0006811 | ion transport |
| cellular component | GO:0016021 | integral component of membrane |
| biological process | GO:0034220 | ion transmembrane transport |