Position
| Chromosome | chr25 |
| Start | 5981795 |
| End | 6000652 |
| Strand | + |
view in Gbrowse: chr25:5981795..6000652
Most similar sequence in NCBI nr database
| Accession | Description | E-value | Score |
|---|
| XP_004924525.1 | venom carboxylesterase-6 | 0.0 | 1301 |
ORF sequence (1902 bp)
ATGCGCATGTGGTGGCGCGCTTTGTCCATTTGTGCATTCGCATTGGTGCTTCATACAGATGCCCTTCCTCCTGCAACTCTTGGAGATGTTGTTGCCAATGCGGCTTCTAGCCTCAATTCCATGAAGGTGACCGGAGCTTGGAGACGCTTATCTAGCACCGTTAGTGAGTCAGTTGGATTGAAGCACGCCCTGCGAAGATTACAAGCCGTGCCGGCTCGGGCTGCGAGACTGGTCCACGCCTTGGTAGACCGTATGAGAGTCGGCGGCGGTCCTATCATCTCAACAAAATATGGTGCTCTGCGTGGTCGAAAGCTTGTTACTCGTACCACCAGCCAAACTCCTTACTACAGCTTCAAAGGAATTAGGTATGCGCAACCGCCGCACGGGTCTCTGCGTTTCCGACCTCCAGTTCAATTGGAGCCCTGGTCAGGGGTCCGGGATGCGCTAGAAGAAGGAGCAGTCTGCCCTCATCGGTTTATGTTATTTGATACATATAAGGGCGATGAGGATTGTCTCTTCCTAAACGTATATACTCCAGCGTTGCCTGATAATATTTCTGGGTACAATCCAAAATTAGCCGTAATGGTTTGGATCCACGGTGGGGCTTTCGCGGTTGGATCCGGCAATGCTTTCTTGTACGGTCCTGACCATTTGGTCGGCGCTGGAGTAGTTCTGGTCACCCTAAACTACAGGCTTGGAGCTCTCGGCTTTTTAAGCCTCGAAAACGAAGAAGTCCCTGGCAATATGGGACTCAAAGATCAAGTAATGGCTCTCAAATGGGTACGAGACAATATTGAGGCATTTGGCGGCGACTCGTCTCGAGTCACAATCTTCGGGGAATCCGCTGGTGCAGCCTCCGTACACCTTCATATGCTTTCACCGGCCTCACGGGGTTTGTTTCATGGAGCCATAGCTGAAAGCGGCGTGGCCCTGTCTCCGTGGGCACTCGCACAACAACCTCGAGAGCGTGCCTTCGAACTCGGCAGAGAGCTTGGTATCGACACCAACAGTACAGCAGAATTACTAGGGTATCTCCGCGCGACTCCGAGCGAGTTGCTAGTGAAGGCGGGAGCGAGACTGGCAGGAGCTCCTGGTAAATCAGCCGATCTACAGAGCACAGTCGCGCTGCCATTCTTACCGGCCGTCGAGCCTGACTTGCCAGACTCATTCCTCACTGAAACTCCGAGAAACTCTCTCCCGGGAGCAGACGTACCGTTTCTGACAGGATACAACGCACAGGAAGGCTTAATTTTATTTCGACGTTTACAACGCTATCCGAAGTTGCTGGTAGAATTGGACCAAGAGTTCAAACGAGTGGTCCCACCGGAGTTACTTCAGCAAAACGTTACCCTAAACCAAAAAATAACGGACGTCATCAGGGCATTCTACTTCCAACAAAGACCTGTCGATGTTAGAAACATTGACAGTCTGATTGATCTATTCACGGACGTCATGTTCTTGAGGCCGACGTTGGAGACCGTGCGGCTTTACGGCGCTAGCAACAGAACTAGTCCAACATATTTATATCGGTTCGCATTCGACGGCGCCCTGGGTCTCTTCAAACGGATGCTGGGTATTACGCACCCAGGAGCCTGTCACGGCGACGAAATGGGATACCTGTTTTATTTCTCGAGAATAAATTACAGATTAGACGAAGGTTCCACGGAATGGGCCGTATCGAAGAAAATGGTACAAATGTGGACTAACTTTGCTAAAACCGGAAATCCGACACCACCGGTCGATTACGAGTCTATTGTAGATTTTAAATGGTTACCTGTAAATGAGAGTTCGCACGTCAACTATCTAGATATCACTGGGAACTTTACATCGAAAGTGGACCCCGAGCAGAGGAGAATCAATTTTTGGGACTGGCTCTACGAGAATTTTGCGAAAAAACCTTGA
Protein sequence (633 aa)
MRMWWRALSICAFALVLHTDALPPATLGDVVANAASSLNSMKVTGAWRRLSSTVSESVGLKHALRRLQAVPARAARLVHALVDRMRVGGGPIISTKYGALRGRKLVTRTTSQTPYYSFKGIRYAQPPHGSLRFRPPVQLEPWSGVRDALEEGAVCPHRFMLFDTYKGDEDCLFLNVYTPALPDNISGYNPKLAVMVWIHGGAFAVGSGNAFLYGPDHLVGAGVVLVTLNYRLGALGFLSLENEEVPGNMGLKDQVMALKWVRDNIEAFGGDSSRVTIFGESAGAASVHLHMLSPASRGLFHGAIAESGVALSPWALAQQPRERAFELGRELGIDTNSTAELLGYLRATPSELLVKAGARLAGAPGKSADLQSTVALPFLPAVEPDLPDSFLTETPRNSLPGADVPFLTGYNAQEGLILFRRLQRYPKLLVELDQEFKRVVPPELLQQNVTLNQKITDVIRAFYFQQRPVDVRNIDSLIDLFTDVMFLRPTLETVRLYGASNRTSPTYLYRFAFDGALGLFKRMLGITHPGACHGDEMGYLFYFSRINYRLDEGSTEWAVSKKMVQMWTNFAKTGNPTPPVDYESIVDFKWLPVNESSHVNYLDITGNFTSKVDPEQRRINFWDWLYENFAKKP
Domains and motifs
| Database | ID | Description | Start | End | Evalue | InterPro ID |
|---|
| Gene3D | 3.40.50.1820 | - |
68 | 632 | 0.0 |
IPR029058 |
| PANTHER | PTHR43142 | - |
90 | 631 | 0.0 |
- |
| PANTHER | PTHR43142:SF1 | - |
90 | 631 | 0.0 |
- |
| Pfam | PF00135 | Carboxylesterase family |
91 | 622 | 0.0 |
IPR002018 |
| SUPERFAMILY | SSF53474 | - |
91 | 626 | 0.0 |
IPR029058 |
| CDD | cd00312 | Esterase_lipase |
92 | 605 | 1.1e-157 |
- |
| ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. |
169 | 179 | - |
IPR019819 |
| ProSitePatterns | PS01173 | Lipolytic enzymes "G-D-X-G" family, putative histidine active site. |
195 | 211 | - |
IPR002168 |
| ProSitePatterns | PS00122 | Carboxylesterases type-B serine active site. |
268 | 283 | - |
IPR019826 |
InterPro assignment
| InterPro ID | InterPro description |
|---|
| IPR002018 | Carboxylesterase, type B |
| IPR002168 | Lipase, GDXG, putative histidine active site |
| IPR019819 | Carboxylesterase type B, conserved site |
| IPR019826 | Carboxylesterase type B, active site |
| IPR029058 | Alpha/Beta hydrolase fold |
Gene ontology (GO) assignment
| GO category | GO ID | GO description |
|---|
| molecular function | GO:0016787 | hydrolase activity |